anti-Paxillin LD4

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The anti-human Paxillin LD4 FluorAbody binds the leucine rich motif LD4 at the N-terminus of Paxillin. This FluorAbody can be used to visualize Paxillin in focal adhesion in cells and selectively to inhibit FAK binding to LD4 region of Paxillin. It is monovalent and only binds one epitope , and thus allows stoichiometric quantitation of the antigen in vitro. It can be imaged on a properly equipped fluorescent microscope as well as detected in a flow cytometer or other fluorometric system. At 50-52 kD it is roughly 1/3 the size of an IgG antibody making it less likely to cause steric hindrance. Due to being recombinant and intrinsically fluorescent, each antibody lot is identical to the next, eliminating the necessity for re-titration.

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SKU 31004110
Binding Domain anti-Paxillin LD4

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